Q1. The main nitrogenous waste products excreted by the human kidney are _____.
- (a) Carbon dioxide and Oxygen
- (b) Urea and Uric acid
- (c) Amino acids and Glucose
- (d) Fatty acids and Glycerol
Answer & solution
Answer: (b) Urea and Uric acid
The main nitrogenous waste products excreted by the human kidney are urea and uric acid. Urea: The primary nitrogenous waste in humans; produced in the liver through the urea cycle (ornithine cycle) from the breakdown of amino acids (deamination); urea is filtered from the blood by the kidneys and excreted in urine; approximately 25-30 grams of urea is excreted daily; Uric acid: Produced from the breakdown of purine nucleotides (adenine and guanine from DNA/RNA); also filtered and excreted by the kidneys; elevated uric acid levels cause gout (a painful joint condition due to uric acid crystal deposition); Other nitrogenous compounds in urine: Creatinine (from muscle metabolism), ammonia (very small amounts — toxic), urea (majority — about 80-90% of total nitrogen excretion); Types of excretion based on waste product: Ammonotelic (ammonia — aquatic animals like fish), Ureotelic (urea — mammals including humans, amphibians), Uricotelic (uric acid — birds, reptiles, insects — conserve water). Humans are primarily UREOTELIC but also excrete uric acid.
Option (a) Carbon dioxide and Oxygen — Incorrect: Carbon dioxide is a waste product of cellular respiration but is eliminated through the lungs (respiratory system), NOT the kidneys; oxygen is not a waste product — it is essential for life; the main nitrogenous wastes excreted by the kidney are urea and uric acid.
Option (c) Amino acids and Glucose — Incorrect: Amino acids and glucose are valuable nutrients that are normally reabsorbed back into the blood by the kidney tubules; they appear in urine only in disease conditions (like diabetes mellitus for glucose); they are NOT the main nitrogenous waste products excreted by the kidneys.
Option (d) Fatty acids and Glycerol — Incorrect: Fatty acids and glycerol are products of fat digestion and are metabolized for energy; they are not nitrogenous compounds and are NOT excreted as waste by the kidneys; the main nitrogenous wastes are urea and uric acid.