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Heredity and Evolution PYQs – Biology, SSC & Railway

76 Heredity and Evolution (Biology) questions asked in recent SSC and Railway exams, newest first, with exam, date & shift, answers and solutions.

📚 76 questionsSSC 15 · Railway 61
SSC Stenographer 2026 – 10 September 2026 Shift 1 · Evidences of evolution (homologous and analogous organs, fossils)

Q1. Which of the following is an example of an homologous organ?

  1. (a) Wings of a bird and wings of a butterfly
  2. (b) Flippers of a whale and forelimbs of a human
  3. (c) Eyes of an octopus and eyes of a human
  4. (d) Sweet potato and potato (as storage organs)
Answer & solution

Answer: (b) Flippers of a whale and forelimbs of a human

Answer: Option 2 — Flippers of a whale and forelimbs of a human
Homologous organs share the same basic structure and embryonic origin but do different jobs.
A whale's flipper and a human arm are both built on the same pentadactyl forelimb plan — humerus, radius, ulna, carpals, metacarpals and phalanges.
Revision note — Evidence of evolution
• Homologous organs — same structure and origin, different function: the forelimbs of a whale, bat, horse, cat and human.
• In plants, the thorn of Bougainvillea and the tendril of Cucurbita are homologous — both are modified stems.
• Homology points to a common ancestor and is the mark of divergent evolution.
• Analogous organs — different structure and origin, same function: the wings of a bird and of an insect, the eye of an octopus and of a human. These show convergent evolution.
• Vestigial organs are reduced, functionless remains: in humans the vermiform appendix, the nictitating membrane, wisdom teeth and the coccyx.
• Fossils give direct evidence — Archaeopteryx is the connecting link between reptiles and birds.
• Embryology (all vertebrate embryos show gill slits and a tail) and biochemistry (the shared DNA and protein code) are further lines of evidence.
Do not mix these up
• Homologous vs analogous — homologous means same structure, different function (divergent evolution); analogous means different structure, same function (convergent evolution).
• Sweet potato vs potato — the sweet potato is a modified root and the potato a modified stem, so although both store food they are analogous, not homologous.
Also asked from this topic: Darwin's “descent with modification” (populations change genetically through natural selection); what small variations over many generations produce (the evolution of biodiversity).

Q2. Which of the following statements best describes the transcriptome, its biological significance, and its distinction from the genome and proteome in cellular function analysis?

  1. (a) The transcriptome refers to the complete set of proteins synthesized by a cell, helping determine the final phenotype regardless of gene expression levels.
  2. (b) The transcriptome comprises only the DNA sequences of coding genes and remains constant across different cell types and developmental stages.
  3. (c) The transcriptome is the full range of RNA molecules—including mRNA, rRNA, tRNA, and non-coding RNAs—transcribed from the genome at a given time, and its dynamic nature allows insight into gene expression regulation, cell differentiation, and disease mechanisms.
  4. (d) The transcriptome includes all epigenetic modifications on DNA and histone proteins that regulate transcription without altering the RNA sequence, making it a part of the permanent genetic code.
Answer & solution

Answer: (c) The transcriptome is the full range of RNA molecules—including mRNA, rRNA, tRNA, and non-coding RNAs—transcribed from the genome at a given time, and its dynamic nature allows insight into gene expression regulation, cell differentiation, and disease mechanisms.

Answer: Option 3 — The transcriptome is the full range of RNA molecules transcribed from the genome at a given time
The transcriptome is every RNA molecule — mRNA, rRNA, tRNA and non-coding RNAs — present in a cell at one moment.
Unlike the fixed genome it is dynamic, changing with cell type, developmental stage and disease, which is what makes it a window on gene expression.
Revision note — Genome, transcriptome and proteome
• Central dogma: DNA → RNA → protein. Making RNA from DNA is transcription; making protein from mRNA is translation.
• Genome = the complete DNA of an organism. It is the same in every body cell and does not vary with tissue or age.
• Transcriptome = all RNA transcribed at a given time. It is measured by RNA-seq and microarrays and differs from tissue to tissue.
• Proteome = the complete set of proteins a cell makes; epigenome = the chemical marks such as DNA methylation and histone modification that switch genes on and off without changing the DNA sequence.
• RNA polymerase carries out transcription. RNA has the sugar ribose and the base uracil (U); DNA has deoxyribose and thymine (T).
• mRNA carries the message, tRNA brings amino acids to the ribosome, and rRNA builds the ribosome itself.
Do not mix these up
• Transcriptome vs proteome — RNA against protein; the proteome is one step further down the central dogma.
• Transcriptome vs epigenome — methylation and histone marks are the epigenome, not RNA.
• Transcription vs translation — transcription makes RNA from DNA; translation makes protein from RNA.
Also asked from this topic: the flow of genetic information (DNA → RNA → protein); what happens in transcription (DNA is copied into RNA); when the human genome was sequenced (2003).

Q3. DNA, which is also called __________ acid, is the hereditary material that carries genetic information in cells.

  1. (a) Denatured
  2. (b) Deoxyribonucleic
  3. (c) Di-ribonucleic
  4. (d) Decarbonated
Answer & solution

Answer: (b) Deoxyribonucleic

Correct Answer:
Option 2 – Deoxyribonucleic
Explanation:
DNA stands forDeoxyribonucleic Acid. It is the hereditary material present in the nucleus (and some organelles) of cells that carries genetic information from one generation to the next.
Important Facts:
• DNA has a double helix structure, discovered by Watson and Crick (1953).
• RNA (Ribonucleic Acid) is the other nucleic acid, involved in protein synthesis.
Correct Answer: Option 2 – Deoxyribonucleic
RRB Group D 2025-26 – 12 August 2026 Shift 1 · Theories of evolution (Lamarck, Darwin)

Q4. A researcher is studying how small differences among individuals over generations contribute to the emergence of new life forms. Which process does this scenario illustrate?

  1. (a) Taxonomic classification
  2. (b) Evolution of biodiversity
  3. (c) Ecological succession
  4. (d) Genetic drift
Answer & solution

Answer: (b) Evolution of biodiversity

Answer: Option 2 – Evolution of biodiversity.
• Small heritable variations accumulating over generations to form new species isevolution.

Q5. A scientist wants to ensure that a human zygote formed in a laboratory dish has the correct number of chromosomes. Number of chromosomes this zygote should have are:

  1. (a) 23
  2. (b) 69
  3. (c) 46
  4. (d) 92
Answer & solution

Answer: (c) 46

Answer: Option 3 – 46.
• A human zygote (fertilised egg) is diploid with46 chromosomes(23 from each parent).

Q6. Two siblings from the same parents often look different from each other. Which process mainly causes this difference?

  1. (a) Photosynthesis
  2. (b) Mitosis
  3. (c) Meiosis
  4. (d) Respiration
Answer & solution

Answer: (c) Meiosis

Answer: Option 3 – Meiosis.
•Meiosis(with crossing over and independent assortment) produces genetically varied gametes, so siblings differ from one another.

Q7. Which molecule is primarily responsible for storing genetic information in most living organisms?

  1. (a) RNA
  2. (b) Lipid
  3. (c) Protein
  4. (d) DNA
Answer & solution

Answer: (d) DNA

Topic: Genetic Material in Living Organisms
DNA (Deoxyribonucleic Acid)is the primary genetic material in most organisms.
DNA stores hereditary information in the form of genes.
RNA stores genetic information only in some viruses.
Proteins and lipids do not store genetic information.
Answer: Option 4 → DNA

Q8. Tallness in pea plants as identified by Mendel, represents which type of trait?

  1. (a) Recessive traits
  2. (b) Dominant traits
  3. (c) Hidden traits
  4. (d) Acquired traits
Answer & solution

Answer: (b) Dominant traits

Mendel's Pea Plant Experiment
Mendel crossed tall (TT) and dwarf (tt) pea plants.
F1 generation: All plants were tall (Tt).
This showedtallness is dominantover dwarfness.
Dominant trait: Expressed even in heterozygous condition (Tt).
Recessive trait (dwarfness): Only expressed in homozygous (tt).
Answer: Option 2 → Dominant traits

Q9. The phenotype short in pea plants is expressed by which allele combination?

  1. (a) tT
  2. (b) TT
  3. (c) tt
  4. (d) Tt
Answer & solution

Answer: (c) tt

Mendelian Genetics - Height in Pea Plants
Tall (T) is dominant over short (t)
Phenotype expression:
TT → Tall (homozygous dominant)
Tt or tT → Tall (heterozygous)
tt → Short (homozygous recessive)
Short phenotype appears only when both alleles are recessive
Answer: Option 3 → tt
RRB NTPC UG CBT-1 2025-26 – 7 May 2026 Shift 2 · Genetic terms (dominant, recessive, genotype, phenotype)

Q10. In a cross between true-breeding red-flowered and true breeding white-flowered plants, the Filial 1 (F₁) progeny was pink. This is a case of which type of inheritance?

  1. (a) Complete Dominance
  2. (b) Incomplete Dominance
  3. (c) Co-dominance
  4. (d) Sex-linkage
Answer & solution

Answer: (b) Incomplete Dominance

Cross: Red (RR) × White (WW)
F₁ progeny: All pink flowers (RW)
Incomplete Dominance:
Neither allele is completely dominant
Heterozygote shows intermediate phenotype
Red + White = Pink (blended)
Complete dominance → F₁ would be red
Co-dominance → Both colors expressed separately
Answer: Option 2 → Incomplete Dominance

Q11. In genetics, a gene refers to which of the following?

  1. (a) A unit of blood group
  2. (b) A sex chromosome
  3. (c) A type of chromosome
  4. (d) A section of DNA that codes for a protein
Answer & solution

Answer: (d) A section of DNA that codes for a protein

Topic: Genetics - Gene Definition
Gene:A specific segment of DNA that contains instructions for making proteins.
Key Facts:
• Genes are functional units of heredity located on chromosomes
• Each gene codes for a specific protein or functional RNA
• DNA → Gene → Protein (Central Dogma)
Other options incorrect:
• Blood group is determined by genes, not a gene itself
• Sex chromosomes (X, Y) contain many genes
• Chromosome is made up of many genes
Answer: Option 4 → A section of DNA that codes for a protein
SSC GD 2026 – 5 May 2026 Shift 1 · Chromosomes, genes and DNA

Q12. Humans have a total of 46 chromosomes. How many pairs of autosomes (non-sex chromosomes) are there?

  1. (a) 20
  2. (b) 22
  3. (c) 23
  4. (d) 21
Answer & solution

Answer: (b) 22

Correct Answer: 22 — Option (b)
Humans have 46 chromosomes arranged in 23 pairs. Of these, 22 pairs are autosomes (non-sex chromosomes), and 1 pair consists of sex chromosomes (XX in females, XY in males). Autosomes carry genes responsible for most bodily traits. Each autosome pair is numbered 1 through 22 by size, with chromosome 1 being the largest. Abnormalities in autosomes can cause conditions like Down syndrome (extra chromosome 21).
Option (a) 20 — Incorrect: Humans have 22 pairs of autosomes, not 20.
Option (c) 23 — Incorrect: While humans have 23 pairs of chromosomes in total, only 22 of these are autosomes; the 23rd pair is the sex chromosomes.
Option (d) 21 — Incorrect: There are 22 autosome pairs in humans, not 21.
RRB NTPC GL CBT-1 2025-26 – 24 March 2026 Shift 2 · Genetic terms (dominant, recessive, genotype, phenotype)

Q13. What are the different forms of a gene called?

  1. (a) Genotypes
  2. (b) Chromosomes
  3. (c) Phenotypes
  4. (d) Alleles
Answer & solution

Answer: (d) Alleles

Topic:Genetics - Gene Forms
Allelesare alternative forms of the same gene.
They occupy the same position (locus) on homologous chromosomes.
Example: Gene for eye color has alleles for brown, blue, green.
Other terms:
Genotype = genetic makeup (combination of alleles)
Phenotype = physical expression of genes
Chromosomes = structures containing many genes
Answer: Option 4 → Alleles

Q14. The intermediary that DNA molecules use to communicate with the rest of the cell is the:

  1. (a) tRNA
  2. (b) miRNA
  3. (c) rRNA
  4. (d) mRNA
Answer & solution

Answer: (d) mRNA

Central Dogma of Molecular Biology:
DNA → mRNA → Protein
Key Facts:
1.mRNA (messenger RNA)carries genetic information from DNA to ribosomes
2. Acts as intermediary between DNA (nucleus) and protein synthesis machinery
3. tRNA brings amino acids, rRNA forms ribosomes, miRNA regulates genes
Function:mRNA transcribes DNA code and translates it into proteins
Answer: Option 4 → mRNA

Q15. Which law of Mendel explains the separation of alleles during gamete formation?

  1. (a) Law of Assortment
  2. (b) Law of Variation
  3. (c) Law of Dominance
  4. (d) Law of Segregation
Answer & solution

Answer: (d) Law of Segregation

Mendel's Law of Segregation
This law states that paired alleles separate during gamete formation.
Each gamete receives only one allele from each pair.
During meiosis, homologous chromosomes separate.
Each gamete gets one allele randomly.
Answer: Option 4 → Law of Segregation
RRB NTPC GL CBT-1 2025-26 – 17 March 2026 Shift 2 · Monohybrid and dihybrid crosses

Q16. What is the purpose of the Punnett square in genetics?

  1. (a) Predicting the outcomes of genetic crosses
  2. (b) Determining the phenotype of an individual
  3. (c) Identifying the location of a gene on a chromosome
  4. (d) Analysing DNA replication
Answer & solution

Answer: (a) Predicting the outcomes of genetic crosses

A Punnett square is a diagram used to predict the genotypes and phenotypes of offspring from a genetic cross.
It shows all possible combinations of alleles from parents.
Helps calculate probability of traits in offspring.
Answer: Option 1 → Predicting the outcomes of genetic crosses
RRB NTPC GL CBT-1 2025-26 – 16 March 2026 Shift 3 · Monohybrid and dihybrid crosses

Q17. The F2 generation of a monohybrid cross typically shows which phenotypic ratio?

  1. (a) 1:1
  2. (b) 2:1
  3. (c) 1:2:1
  4. (d) 3:1
Answer & solution

Answer: (d) 3:1

In a monohybrid cross (Aa × Aa):
F2 Genotype ratio = 1 AA : 2 Aa : 1 aa (1:2:1)
F2 Phenotype ratio = 3 Dominant : 1 Recessive (3:1)
Because AA and Aa both express the dominant phenotype (3 out of 4),
while aa expresses the recessive phenotype (1 out of 4).
Answer: Option 4 → 3:1

Q18. What is the importance of sexual reproduction in creating variation in plant populations?

  1. (a) It mixes DNA from two parents to create new variations.
  2. (b) It prevents any variations from occurring.
  3. (c) It copies DNA without any changes.
  4. (d) It speeds up DNA copying errors.
Answer & solution

Answer: (a) It mixes DNA from two parents to create new variations.

Sexual reproduction combines genetic material from two parent plants.
This mixing creates new gene combinations in offspring.
These new combinations cause variation in the plant population.
Variation is important for adaptation and evolution.
Thus, sexual reproduction increases genetic diversity in plants.

Q19. Which of the following statements best aligns with the concept of 'descent with modification' as described in Darwin's theory of evolution?

  1. (a) Traits acquired during an organism's lifetime are inherited by its offspring.
  2. (b) All species are fixed and do not change over time.
  3. (c) Populations change genetically over generations due to differential survival and reproduction.
  4. (d) Mutations alone are responsible for evolutionary change.
Answer & solution

Answer: (c) Populations change genetically over generations due to differential survival and reproduction.

Option c is correct . 'Descent with modification' is the core idea of Darwin's theory: populations of organisms change genetically over successive generations through the process of natural selection — individuals with traits better suited to their environment survive longer and reproduce more, passing on those advantageous traits.
• Option 1 is wrong: This describes Lamarckism (inheritance of acquired characteristics), which Darwin's theory replaced.
• Option 2 is wrong: This is the pre-Darwinian (creationist/fixist) view that species are immutable.
• Option 4 is wrong: While mutations are a source of genetic variation, Darwin's theory emphasizes natural selection acting on variation, not mutations alone driving evolution.

Q20. Which nitrogenous base is found in RNA but replaced by thymine in DNA molecules?

  1. (a) Adenine
  2. (b) Uracil
  3. (c) Guanine
  4. (d) Cytosine
Answer & solution

Answer: (b) Uracil

The correct answer is (b) Uracil.
Uracil (U) is a pyrimidine nitrogenous base found in RNA. In DNA, Uracil is replaced by Thymine (T). Both Uracil and Thymine pair with Adenine (A) through hydrogen bonds. The presence of Thymine (instead of Uracil) in DNA makes DNA more chemically stable, as Thymine is a methylated form of Uracil.
(a) Adenine: A purine base found in BOTH DNA and RNA; it pairs with Thymine in DNA and Uracil in RNA; Adenine is NOT replaced by Thymine.
(c) Guanine: A purine base found in BOTH DNA and RNA; it pairs with Cytosine; Guanine is not replaced by Thymine.
(d) Cytosine: A pyrimidine base found in BOTH DNA and RNA; it pairs with Guanine; Cytosine is not replaced by Thymine.

Q21. Which enzyme joins Okazaki fragments on the lagging strand during DNA replication to create a continuous DNA strand?

  1. (a) Helicase
  2. (b) Ligase
  3. (c) Primase
  4. (d) Polymerase
Answer & solution

Answer: (b) Ligase

The correct answer is (b) Ligase.
DNA Ligase is the enzyme that joins Okazaki fragments on the lagging strand during DNA replication. After DNA Polymerase I removes RNA primers and fills in the gaps with DNA, DNA Ligase seals the nick between adjacent Okazaki fragments by forming phosphodiester bonds, creating a continuous DNA strand.
(a) Helicase: Unwinds and separates the double helix at the replication fork by breaking hydrogen bonds between base pairs; does not join Okazaki fragments.
(c) Primase: Synthesizes short RNA primers on the template strand to initiate DNA synthesis; required before Polymerase can act; does not join Okazaki fragments.
(d) Polymerase: DNA Polymerase III synthesizes the new DNA strand; DNA Polymerase I removes RNA primers; neither joins the final fragments — that is Ligase's role.

Q22. Which of the following is NOT a nitrogenous base in DNA?

  1. (a) Adenine
  2. (b) Uracil
  3. (c) Cytosine
  4. (d) Guanine
Answer & solution

Answer: (b) Uracil

Correct Answer: Uracil (Option 2)
DNA contains four nitrogenous bases: Adenine (A), Thymine (T), Guanine (G), and Cytosine (C). Uracil (U) is found in RNA, where it replaces Thymine. Therefore, Uracil is NOT a nitrogenous base found in DNA.
Adenine, Cytosine, and Guanine are all nitrogenous bases present in both DNA and RNA.
Thymine is exclusive to DNA (replaced by Uracil in RNA).
Uracil is exclusive to RNA (not DNA).

Q23. Given four enzymes:
1. DNA polymerase
2. Ligase
3. Helicase
4. Peptidase.
Which are directly involved in DNA replication?

  1. (a) 1 and 2
  2. (b) 2 and 4
  3. (c) 1, 2 and 3
  4. (d) 3 and 4
Answer & solution

Answer: (c) 1, 2 and 3

Correct Answer: 1, 2 and 3
DNA Polymerase (1): Directly involved — synthesizes new DNA strands.
Ligase (2): Directly involved — joins Okazaki fragments on the lagging strand.
Helicase (3): Directly involved — unwinds the DNA double helix at the replication fork.
Peptidase (4): NOT involved in DNA replication — it is a protease that breaks down peptide bonds in proteins.
Therefore, enzymes 1, 2, and 3 are directly involved in DNA replication.

Q24. Which enzyme primarily is responsible for joining "Okazaki fragments" during the DNA replication process?

  1. (a) DNA polymerase
  2. (b) DNA ligase
  3. (c) Helicase
  4. (d) Primase
Answer & solution

Answer: (b) DNA ligase

Correct Answer: DNA ligase
Okazaki fragments are short segments of newly synthesized DNA on the lagging strand during DNA replication. Once the RNA primers are removed and gaps are filled by DNA polymerase, DNA ligase joins (seals) these fragments together by forming phosphodiester bonds, creating a continuous strand.
Option 1 (DNA polymerase): Incorrect. DNA polymerase synthesizes new DNA but cannot join fragments.
Option 3 (Helicase): Incorrect. Helicase unwinds the double helix at the replication fork.
Option 4 (Primase): Incorrect. Primase synthesizes RNA primers to initiate DNA replication.

Q25. Arrange these evolutionary events chronologically:
A. First eukaryotes
B. First prokaryotes
C. Multicellularity
D. Oxygen accumulation

  1. (a) B → D → A → C
  2. (b) A → B → D → C
  3. (c) D → B → A → C
  4. (d) B → A → C → D
Answer & solution

Answer: (a) B → D → A → C

Correct Answer: B → D → A → C
Chronological order of evolutionary events:
B. First prokaryotes: ~3.8–3.5 billion years ago (earliest life forms)
D. Oxygen accumulation: ~2.4 billion years ago (Great Oxidation Event, caused by cyanobacteria)
A. First eukaryotes: ~2–1.8 billion years ago (after oxygen accumulation enabled complex cells)
C. Multicellularity: ~1 billion years ago (eukaryotic cells grouped into multicellular organisms)
Thus, the correct order is B → D → A → C.

Q26. In the lac operon model, what is the primary role of the allolactose molecule?

  1. (a) It acts as a corepressor, binding with the repressor protein.
  2. (b) It binds to the promoter to initiate transcription.
  3. (c) It functions as an inducer, binding to the repressor protein and inactivating it.
  4. (d) It directly codes for the enzymes involved in lactose metabolism.
Answer & solution

Answer: (c) It functions as an inducer, binding to the repressor protein and inactivating it.

The correct answer is option 3. In the lac operon model of prokaryotic gene regulation (studied in E. coli ), allolactose acts as an inducer molecule . When lactose is available, a small portion of it is converted into allolactose, which binds to the repressor protein . Normally, the repressor binds to the operator region and blocks transcription of lactose-metabolizing genes. However, when allolactose binds to the repressor, it changes the repressor’s shape, preventing it from attaching to the operator. This inactivation allows RNA polymerase to transcribe the genes responsible for lactose metabolism.

Q27. Which of the following sequences correctly represents flow of genetic info?

  1. (a) DNA → Protein → RNA
  2. (b) RNA → DNA → Protein
  3. (c) DNA → RNA → Protein
  4. (d) Protein → RNA → DNA
Answer & solution

Answer: (c) DNA → RNA → Protein

According to the central dogma of molecular biology, genetic information flows from DNA → RNA → Protein (transcription followed by translation).
SSC CGL Tier-1 2025 – 14 September 2025 Shift 1 · Genetic terms (dominant, recessive, genotype, phenotype)

Q28. The term 'pleiotropy' refers to:

  1. (a) One gene affects multiple traits
  2. (b) Multiple genes affect one trait
  3. (c) Gene mutation in one allele
  4. (d) Gene duplication
Answer & solution

Answer: (a) One gene affects multiple traits

Pleiotropy is the phenomenon in genetics where a single gene influences two or more apparently unrelated phenotypic traits — i.e., one gene affects multiple traits.
Multiple genes affecting one trait is polygenic inheritance.
Gene mutation in one allele is simply a point mutation; gene duplication is a separate genetic event.
Hence pleiotropy = one gene affecting multiple traits.

Q29. What is the primary function of telomerase enzyme?

  1. (a) DNA replication
  2. (b) Telomere lengthening
  3. (c) DNA repair
  4. (d) RNA transcription
Answer & solution

Answer: (b) Telomere lengthening

Telomerase is a ribonucleoprotein enzyme that adds repetitive nucleotide sequences (TTAGGG in humans) to the ends of chromosomes (telomeres).
This lengthening of telomeres compensates for the gradual shortening that occurs with each round of DNA replication.
DNA replication is done mainly by DNA polymerases; DNA repair involves different enzymes; RNA transcription is performed by RNA polymerase.
Hence the primary function of telomerase is telomere lengthening.

Q30. Which pair of scientists first proposed the double-helix model for the structure of DNA?

  1. (a) Mendel and Avery
  2. (b) Darwin and Wallace
  3. (c) Franklin and Chargaff
  4. (d) Watson and Crick
Answer & solution

Answer: (d) Watson and Crick

RRB NTPC UG CBT-1 2024-25 – 2 September 2025 Shift 2 · Genetic terms (dominant, recessive, genotype, phenotype)

Q31. Which of the following terms describe a change in the DNA sequence resulting in changes in the genotype and the phenotype of an organism?

  1. (a) Dominance
  2. (b) Transcription
  3. (c) Segregation
  4. (d) Mutation
Answer & solution

Answer: (d) Mutation

Q32. The process by which traits are passed from parents to offspring is known as _____________.

  1. (a) mutation
  2. (b) heredity
  3. (c) hybridisation
  4. (d) linkage
Answer & solution

Answer: (b) heredity

RRB NTPC UG CBT-1 2024-25 – 21 August 2025 Shift 3 · Monohybrid and dihybrid crosses

Q33. Which of the following options best represents the predictions of a Punnett square?

  1. (a) Genetic linkage relationships in siblings
  2. (b) Genotype and phenotype probabilities
  3. (c) DNA sequence in parents
  4. (d) Genetic mutations over several generations
Answer & solution

Answer: (b) Genotype and phenotype probabilities

Q34. The Human Genome Project, launched in 1990, had the goal of determining the sequence of how many billion base pairs that make up human DNA?

  1. (a) 4.3 billion
  2. (b) 3.0 billion
  3. (c) 2.1 billion
  4. (d) 5.2 billion
Answer & solution

Answer: (b) 3.0 billion

Q35. When did the Hershey-Chase experiment provide solid evidence that DNA, not proteins, is the genetic material?

  1. (a) 1957
  2. (b) 1952
  3. (c) 1946
  4. (d) 1950
Answer & solution

Answer: (b) 1952

Q36. What happens during the process of transcription in cells?

  1. (a) DNA is replicated into identical copies
  2. (b) RNA is translated into proteins
  3. (c) DNA is converted into RNA
  4. (d) Proteins are folded into functional shapes
Answer & solution

Answer: (c) DNA is converted into RNA

Correct Answer: Option 3 – DNA is converted into RNA
Transcription is the first step of gene expression, in which a specific segment of DNA is copied into messenger RNA (mRNA) by the enzyme RNA polymerase. The mRNA then carries the genetic code from the nucleus to the ribosomes for protein synthesis. The central dogma of molecular biology is: DNA → RNA (Transcription) → Protein (Translation).
Option 1 (DNA replicated into identical copies): This describes DNA Replication, not transcription.
Option 2 (RNA translated into proteins): This describes Translation, the second step after transcription.
Option 4 (Proteins folded into functional shapes): This describes protein folding (post-translational modification), which occurs after translation.

Q37. Which of the following statements about DNA and RNA is true?

  1. (a) DNA acts only as a messenger molecule.
  2. (b) RNA has multiple roles including catalytic functions.
  3. (c) DNA is not present in viruses.
  4. (d) RNA acts solely as genetic material in all living organisms.
Answer & solution

Answer: (b) RNA has multiple roles including catalytic functions.

Q38. Which of the following organisms has the smallest DNA length listed?

  1. (a) Bacteriophage λ
  2. (b) Human haploid cell
  3. (c) φ X174 phage
  4. (d) Escherichia coli
Answer & solution

Answer: (c) φ X174 phage

Q39. Which of the following best explains the functional diversity of RNA molecules in cells?

  1. (a) Their permanent role as genetic material
  2. (b) Their linear sequence of deoxyribonucleotides
  3. (c) Their ability to form double-stranded helical structures
  4. (d) Their capability to act as adapter, structural and catalytic molecules
Answer & solution

Answer: (d) Their capability to act as adapter, structural and catalytic molecules

Q40. What makes DNA the most abundant genetic material?

  1. (a) Its stable double-helical structure
  2. (b) Its high mutation rate
  3. (c) Its interaction with proteins
  4. (d) Its enzymatic roles
Answer & solution

Answer: (a) Its stable double-helical structure

Q41. The complete sequencing of the human genome has marked the beginning of:

  1. (a) immunology
  2. (b) genomics
  3. (c) cytogenetics
  4. (d) structural biology
Answer & solution

Answer: (b) genomics

Q42. Which of the following best describes the impact of human genome sequencing?

  1. (a) It eliminated the need for classical genetics.
  2. (b) It clarified all RNA-related functions.
  3. (c) It marked a milestone toward transcriptional regulation.
  4. (d) It initiated a new scientific domain.
Answer & solution

Answer: (d) It initiated a new scientific domain.

Q43. The mention of DNA as a long polymer of deoxyribonucleotides implies which structural characteristic?

  1. (a) It is composed of a sugar-phosphate backbone and nitrogenous bases.
  2. (b) Each nucleotide is linked by hydrogen bonds in a parallel fashion.
  3. (c) The molecule consists of multiple independent short chains.
  4. (d) The sequence is circular and self-replicating.
Answer & solution

Answer: (a) It is composed of a sugar-phosphate backbone and nitrogenous bases.

Q44. The inability to isolate intact DNA for structural studies prior to the 1950s was primarily due to which molecular feature?

  1. (a) DNA’s large polymeric nature and fragility
  2. (b) DNA’s high melting point
  3. (c) DNA’s interaction with histone proteins
  4. (d) DNA’s susceptibility to UV degradation
Answer & solution

Answer: (a) DNA’s large polymeric nature and fragility

Q45. Which feature of the phosphodiester bond contributes most to the overall negative charge of the DNA molecule?

  1. (a) The methyl group of thymine
  2. (b) The phosphate group’s ionisable oxygen atoms
  3. (c) The nitrogen in purines
  4. (d) The ribose sugar
Answer & solution

Answer: (b) The phosphate group’s ionisable oxygen atoms

Q46. Standard base pairing in DNA occurs due to which type of bonding?

  1. (a) Covalent bonding
  2. (b) Ionic bonding
  3. (c) Hydrogen bonding
  4. (d) Van Der Waals interactions
Answer & solution

Answer: (c) Hydrogen bonding

Q47. DNA polymerase catalyses the addition of nucleotides during DNA replication. Its main role is to:

  1. (a) Synthesise new DNA strands complementary to the template
  2. (b) Remove RNA primers from the lagging strand
  3. (c) Ligate Okazaki fragments together
  4. (d) Unwind the DNA double helix
Answer & solution

Answer: (a) Synthesise new DNA strands complementary to the template

Q48. Which of the following best explains why uracil is used in RNA instead of thymine?

  1. (a) Thymine is not recognized by ribosomes.
  2. (b) Uracil enhances RNA splicing.
  3. (c) Thymine inhibits transcription.
  4. (d) Uracil is energetically cheaper to synthesise.
Answer & solution

Answer: (d) Uracil is energetically cheaper to synthesise.

Q49. The term 'complementary' in the context of DNA refers to which of the following properties?

  1. (a) Matching number of sugar-phosphate units
  2. (b) Identical chemical composition of both strands
  3. (c) Parallel orientation of nucleotide chains
  4. (d) Hydrogen bonding potential based on base specificity
Answer & solution

Answer: (d) Hydrogen bonding potential based on base specificity

Q50. Which of the following organisms has NO genetically predetermined sex?

  1. (a) Snail
  2. (b) Human
  3. (c) Dogs
  4. (d) Pigeon
Answer & solution

Answer: (a) Snail

Correct Answer: Option 1 — Snail
In some animals the sex of the individual is not fixed by chromosomes at all. Snails are such animals — they can change their sex, and the sex is decided by the individual's own condition and surroundings rather than by a genetically predetermined pattern.
In most other animals sex determination is genetic. Human beings have 23 pairs of chromosomes; the 23rd pair is the sex chromosome pair — XX in females and XY in males. Since the mother always gives an X, it is the father's sperm (X or Y) that decides the sex of the child. In some reptiles like turtles and lizards, the temperature of incubation decides the sex.
❌ Why the other options are incorrect
✗ Human — sex is strictly genetic; XX = girl, XY = boy, decided by the father's gamete.
✗ Dogs — mammals with the same XX / XY chromosomal sex determination as humans.
✗ Pigeon — birds use the ZZ / ZW system; the female (ZW) decides the sex of the chick.
📌 SSC & Railway Exam Facts
• Humans have 46 chromosomes (23 pairs) — 22 pairs autosomes + 1 pair sex chromosomes.
• Y chromosome carries the SRY gene that makes an embryo male.
• In Drosophila and humans the male is heterogametic (XY).
• Gregor Johann Mendel is the Father of Genetics; he worked on garden pea (Pisum sativum).
• The temperature-dependent sex determination is seen in turtles and crocodiles.

Q51. ________ is useful for the survival of species over time.

  1. (a) Variation
  2. (b) Population
  3. (c) Budding
  4. (d) Reproduction
Answer & solution

Answer: (a) Variation

Correct Answer: Option 1 — Variation
Variation means the differences that appear among the individuals of a species. It arises from small inaccuracies in DNA copying during reproduction and, in sexual reproduction, from the fresh combinations of genes formed when two gametes fuse.
As NCERT states, variations are useful for the survival of species over time. If a niche changes drastically — the temperature of a water body rises, or a new disease appears — a population of identical individuals could be wiped out entirely. But if some individuals carry a variation, say heat tolerance, they survive and reproduce. Variation is therefore the raw material of natural selection and the basis of evolution.
❌ Why the other options are incorrect
✗ Population — simply the number of individuals of a species living in an area; a large population without variation still perishes if conditions change.
✗ Budding — a method of asexual reproduction (yeast, Hydra) that produces genetically identical clones, hence it actually reduces variation.
✗ Reproduction — it creates copies and maintains the species, but it is the variation generated during reproduction, not the copying itself, that ensures long-term survival.
📌 SSC & Railway Exam Facts
• Sexual reproduction produces more variation than asexual reproduction.
• Charles Darwin gave the theory of natural selection in *The Origin of Species* (1859).
• Gregor Mendel, the Father of Genetics, worked on the garden pea (Pisum sativum).
• Speciation is the formation of new species; genetic drift and geographical isolation aid it.
• Acquired characters are not inherited — proved by August Weismann's mice-tail experiment.

Q52. Genes that control the characteristics of a trait are located on:

  1. (a) vacuoles
  2. (b) chromosomes
  3. (c) endoplasmic reticulum
  4. (d) lysosome
Answer & solution

Answer: (b) chromosomes

Correct Answer: Option 2 — chromosomes
A gene is a segment of DNA that carries the information for one character or trait. These genes are arranged in a definite linear order on thread-like structures called chromosomes, which lie inside the nucleus of the cell. Chromosomes are made of DNA and proteins (histones).
Every human body cell has 23 pairs (46) of chromosomes — one member of each pair coming from the father and the other from the mother. This is exactly why a child shows characters of both parents. Of these, 22 pairs are autosomes and 1 pair is the sex chromosomes (XX in a female, XY in a male), which decide the sex of the child.
❌ Why the other options are incorrect
✗ vacuoles — fluid-filled sacs that provide storage and turgidity; the large central vacuole of a plant cell stores water, sap and wastes. They carry no genes.
✗ endoplasmic reticulum — a membrane network for transport of materials and for making proteins (RER) and lipids (SER); genes are not located on it.
✗ lysosome — the suicide bag of the cell, full of powerful digestive enzymes that clear worn-out organelles; it has no genetic material.
📌 SSC & Railway Exam Facts
• DNA — Deoxyribonucleic acid; its double-helix model was given by Watson and Crick (1953).
• Gregor Mendel is the Father of Genetics; a gene's alternative forms are called alleles.
• The sex of a child is decided by the father, since the mother always gives an X.
• Chromosome number: human 46, pea 14, onion 16, housefly 12.
• The term gene was coined by Johannsen; chromosome was named by Waldeyer.

Q53. Variation is useful for the survival of species over time. These variations occur due to errors in:

  1. (a) DNA copying
  2. (b) differentiation of white blood cells
  3. (c) formation of red blood cells
  4. (d) formation of neurons
Answer & solution

Answer: (a) DNA copying

Correct Answer: Option 1 — DNA copying
Reproduction begins with the copying of DNA in the cell, because DNA carries the blueprint for building the body. The copying is remarkably accurate but never perfect — small errors (mutations) creep in. These errors change the information slightly, and that is the basic source of variation among individuals of a species.
Variation is valuable in the long run. If a population is suddenly hit by a change such as extreme heat, drought or a new disease, the individuals that happen to carry a suitable variation survive and reproduce. Thus variation gives the species a chance of survival and is the raw material for natural selection and evolution.
❌ Why the other options are incorrect
✗ differentiation of white blood cells — WBCs are part of the immune defence of the body; their differentiation is a body function, not an inheritable source of variation.
✗ formation of red blood cells — mature human RBCs have no nucleus and no DNA, so they cannot pass on any change to the next generation.
✗ formation of neurons — neurons conduct nerve impulses; errors here would affect the individual, not the inherited variation of the species.
📌 SSC & Railway Exam Facts
• DNA = Deoxyribo Nucleic Acid, the hereditary material; its double-helix model was given by Watson and Crick (1953).
• A permanent change in the DNA sequence is a mutation.
• Asexual reproduction gives very little variation; sexual reproduction gives much more.
• Charles Darwin proposed natural selection in *On the Origin of Species*.
• Gregor Mendel is the Father of Genetics; he worked on the garden pea (Pisum sativum).

Q54. How many pairs of sex chromosomes are present in humans?

  1. (a) Two pairs
  2. (b) Twenty two pairs
  3. (c) One pair
  4. (d) Forty six pairs
Answer & solution

Answer: (c) One pair

Correct Answer: Option 3 — One pair
A human body cell contains 46 chromosomes, that is 23 pairs. Of these, 22 pairs are autosomes, which carry genes for ordinary body characters, and the remaining one pair is the sex chromosomes, which decide the sex of the individual.
A female has the sex chromosome pair XX, and a male has XY. All eggs made by the mother therefore carry an X chromosome, while the father's sperms are of two kinds — half carrying X and half carrying Y. If an X-bearing sperm fertilises the egg the child is a girl (XX); if a Y-bearing sperm does so the child is a boy (XY). Hence the father's sperm decides the sex of the child, not the mother.
❌ Why the other options are incorrect
✗ Two pairs — humans have only one pair of sex chromosomes; there is no second pair.
✗ Twenty two pairs — 22 pairs are the autosomes, not the sex chromosomes.
✗ Forty six pairs — 46 is the total number of chromosomes, not the number of pairs; 46 pairs would mean 92 chromosomes.
📌 SSC & Railway Exam Facts
• Human somatic cells are diploid (2n = 46); gametes are haploid (n = 23).
• Female = XX, Male = XY; the Y chromosome is the male-determining chromosome.
• Gregor Johann Mendel is the Father of Genetics; he worked on the garden pea (Pisum sativum).
• Haemophilia and colour blindness are X-linked (sex-linked) recessive disorders, commoner in males.
• The term gene was coined by Johannsen; DNA was shown to be the genetic material and its double helix described by Watson and Crick (1953).

Q55. In which of the following organisms can individuals change sex, indicating that sex is NOT genetically determined?

  1. (a) Ostriches
  2. (b) Frogs
  3. (c) Lizards
  4. (d) Snails
Answer & solution

Answer: (d) Snails

Correct Answer: Option 4 — Snails
Sex determination is the process that decides whether a developing individual will be male or female. In most animals this is fixed at the moment of fertilisation by the sex chromosomes inherited from the parents. But in a few animals it is not so rigid.
Snails are the classic NCERT example: an individual snail can change its sex during its life. Since the same individual functions first as one sex and later as the other, its sex clearly cannot be decided by its genes, which never change. This shows that sex determination is not always genetic — in some animals it depends on environmental or physiological factors.
❌ Why the other options are incorrect
✗ Ostriches — like all birds, their sex is fixed genetically by the ZZ (male) / ZW (female) chromosome system; an ostrich cannot switch sex.
✗ Frogs — amphibians have genetically determined sex; an adult frog does not normally change from male to female or the reverse.
✗ Lizards — in many reptiles the incubation temperature of the egg decides the sex, but once the animal is formed that sex stays fixed; lizards do not change sex like snails.
📌 SSC & Railway Exam Facts
• NCERT states that snails can change sex, showing that sex is not always genetically determined.
• In humans the sex chromosomes are XX (female) and XY (male); the father decides the sex of the child.
• Human body cells contain 46 chromosomes (23 pairs) — 22 pairs of autosomes + 1 pair of sex chromosomes.
• In turtles and crocodiles, the temperature at which the fertilised eggs are kept decides the sex of the young.
• The Y chromosome carries the SRY gene, the master switch that triggers male development.

Q56. Which of the following is a dominant trait in the experiment done by Mendel on garden pea?

  1. (a) Round seeds
  2. (b) Wrinkled seeds
  3. (c) Short plants
  4. (d) Green seeds
Answer & solution

Answer: (a) Round seeds

Correct Answer: Option 1 — Round seeds
Gregor Johann Mendel worked on the garden pea (Pisum sativum) and studied seven pairs of contrasting characters. A dominant trait is the one that expresses itself in the F₁ generation and masks the other member of the pair, which is called the recessive trait.
When Mendel crossed a pure round-seeded plant (RR) with a pure wrinkled-seeded plant (rr), all the F₁ plants had round seeds (Rr). Wrinkled seeds reappeared only in the F₂ generation, in a phenotypic ratio of 3 round : 1 wrinkled. Hence round seed shape is the dominant trait and wrinkled is recessive.
❌ Why the other options are incorrect
✗ Wrinkled seeds — the recessive form of seed shape; it disappears in F₁ and reappears in only one-fourth of the F₂ plants.
✗ Short plants — dwarfness is recessive; tallness is the dominant character for plant height in pea.
✗ Green seeds — green colour of the cotyledons is recessive; yellow seed colour is dominant.
📌 SSC & Railway Exam Facts
• Mendel is called the Father of Genetics; he published his work in 1866.
• Dominant characters in pea — round seed, yellow seed, tall plant, violet flower, axial flower, inflated pod, green pod.
• Monohybrid cross — phenotypic ratio 3:1, genotypic ratio 1:2:1; dihybrid cross — 9:3:3:1.
• Mendel's laws — Law of Dominance, Law of Segregation (Law of Purity of Gametes) and Law of Independent Assortment.
• The word gene was coined by W. Johannsen and the word genetics by W. Bateson.

Q57. ________ plays a crucial role in the long-term survival of species.

  1. (a) Growth and development
  2. (b) Fragmentation
  3. (c) Variation
  4. (d) Reproduction
Answer & solution

Answer: (c) Variation

Correct Answer: Option 3 — Variation
Variations are the small differences that appear among individuals of the same species. They arise because DNA copying during reproduction is never perfectly accurate, and also because of recombination of genes during sexual reproduction.
NCERT states that variation is useful for the survival of species over time. If a population is completely uniform and the environment changes suddenly — a rise in temperature, a drought, or a new disease — the entire population could be wiped out. But if variations exist, a few individuals may already possess the character needed to survive the new condition. These survive, reproduce and rebuild the population. Variation therefore gives a species its long-term survival value and provides the raw material for natural selection and evolution.
❌ Why the other options are incorrect
✗ Growth and development — these only increase the size and maturity of an individual; they cannot protect a species against a changing environment.
✗ Fragmentation — a mode of asexual reproduction seen in *Spirogyra*; it produces identical copies and so generates no variation at all.
✗ Reproduction — it certainly continues the species, but by itself, if it made only exact copies, it would not ensure long-term survival; it is the variation arising during reproduction that does.
📌 SSC & Railway Exam Facts
• Sexual reproduction produces far more variation than asexual reproduction.
• Variations arise from errors in DNA copying, mutations and recombination of genes.
• Charles Darwin explained evolution by natural selection in his book *On the Origin of Species* (1859).
• Lamarck gave the theory of inheritance of acquired characters.
• Speciation — the formation of a new species — needs variation, geographical isolation and genetic drift.

Q58. In case of a drastic change in niches of organisms, which of the following can save the population of an organism from getting completely wiped out?

  1. (a) Isolation
  2. (b) Variation
  3. (c) Nutrition
  4. (d) Evolution
Answer & solution

Answer: (b) Variation

Correct Answer: Option 2 — Variation
A niche is the functional role and position of an organism in its habitat — where it lives, what it eats and how it interacts with other species. If the niche changes drastically (a sudden rise in temperature, a new disease, loss of water), most members of a population may be killed.
Variation means the differences in characters found among individuals of the same species. It is produced mainly by sexual reproduction and by small errors in DNA copying during reproduction. A population carrying many variations will almost always contain a few individuals that can tolerate the new conditions. These survivors reproduce, and the species escapes being completely wiped out. Variation therefore gives a population its survival advantage and is the raw material of natural selection.
❌ Why the other options are incorrect
✗ Isolation — geographical separation of two populations; over long periods it leads to speciation, but it cannot protect a population from a sudden change in its niche.
✗ Nutrition — the process of taking in food and using it for energy and growth; it keeps an individual alive but cannot make a whole population tolerant of new conditions.
✗ Evolution — the slow change in inherited characters over many generations; it is the result of variation and selection, not the immediate saviour of a population.
📌 SSC & Railway Exam Facts
• Asexual reproduction produces very few variations; sexual reproduction produces large variation.
• Charles Darwin gave the theory of natural selection in 'On the Origin of Species' (1859).
• Jean-Baptiste Lamarck proposed the inheritance of acquired characters.
• Niche is the functional role of an organism; habitat is only the place where it lives.
• Variations that give a survival advantage are selected by nature and become common in the population.

Q59. Which of the following were found as dominant traits by Mendel in his experiment with pea plants?

  1. (a) Tall plant and round seed
  2. (b) Short plant and wrinkled seed
  3. (c) Tall plant and wrinkled seed
  4. (d) Short plant and round seed
Answer & solution

Answer: (a) Tall plant and round seed

Correct Answer: Option 1 — Tall plant and round seed
Gregor Johann Mendel, the Father of Genetics, worked on the garden pea (*Pisum sativum*) and studied seven pairs of contrasting characters. When he crossed a pure tall plant with a pure dwarf plant, all the plants of the F₁ generation were tall — the dwarf character had disappeared. Likewise, a cross between round and wrinkled seeds gave only round seeds in F₁.
The character that expresses itself in the F₁ hybrid is called the dominant trait, and the one that stays hidden is the recessive trait. So tallness (T) and round seed (R) are dominant, while dwarfness (t) and wrinkled seed (r) are recessive. In the F₂ generation the hidden trait reappears in the ratio 3 : 1.
❌ Why the other options are incorrect
✗ Short plant and wrinkled seed — both are recessive traits; they reappear only in F₂, in one-fourth of the plants.
✗ Tall plant and wrinkled seed — tallness is dominant, but wrinkled seed is recessive, so the pair is wrong.
✗ Short plant and round seed — round seed is dominant, but shortness (dwarfness) is recessive, so the pair is wrong.
📌 SSC & Railway Exam Facts
• Mendel's monohybrid cross gives a phenotypic ratio 3 : 1 and a genotypic ratio 1 : 2 : 1.
• The dihybrid ratio is 9 : 3 : 3 : 1, which gave the Law of Independent Assortment.
• Mendel's laws — Law of Dominance, Law of Segregation (Purity of Gametes) and Law of Independent Assortment.
• Other dominant traits in pea — green pod, axial flower, violet flower; recessive — yellow pod, terminal flower, white flower.
• The word gene was coined by Johannsen; genetics by W. Bateson.

Q60. Which of the following would help a few variants of bacteria in a population living in temperate waters to survive and grow further, if the water temperature were to increased by global warming?

  1. (a) Resistant to wind pressure
  2. (b) Resistant to cold waves
  3. (c) Resistant to water
  4. (d) Resistant to heat
Answer & solution

Answer: (d) Resistant to heat

Correct Answer: Option 4 — Resistant to heat
This is the standard NCERT illustration of variation and natural selection. A population of bacteria is never uniform — small variations arise during DNA copying at reproduction. If the water is heated by global warming, only those few variants that happen to be heat-resistant can survive the new condition; the rest are killed.
The surviving heat-resistant bacteria then reproduce and multiply, so their proportion in the population rises generation after generation. Nature has, in effect, selected them. This is exactly how variation gives a survival advantage and becomes the raw material of evolution, as proposed by Charles Darwin in his theory of natural selection.
❌ Why the other options are incorrect
✗ Resistant to wind pressure — the bacteria live inside water, where wind pressure is not the selecting factor; the change described is a change in temperature.
✗ Resistant to cold waves — this would help if the water became colder; here the water is getting hotter, so cold resistance gives no advantage.
✗ Resistant to water — meaningless for an aquatic organism, since water is its normal habitat, not a stress.
📌 SSC & Railway Exam Facts
• Variation arises from errors in DNA copying and from sexual reproduction.
• Charles Darwin wrote 'On the Origin of Species' (1859) and gave natural selection; Lamarck gave the theory of inheritance of acquired characters.
• Survival of the fittest was the phrase coined by Herbert Spencer.
• Genetic drift changes gene frequency by chance, without any survival advantage.
• Speciation is the formation of a new species; the founder of modern genetics is Gregor Johann Mendel.

Q61. Why is variation in plants important for their survival and evolution?

  1. (a) It allows plants to adapt to changing environmental conditions.
  2. (b) It ensures that all plants produce identical offspring.
  3. (c) It helps plants to grow taller and stronger.
  4. (d) It reduces competition among plants.
Answer & solution

Answer: (a) It allows plants to adapt to changing environmental conditions.

Answer: Option 1 — It allows plants to adapt to changing environmental conditions.
Variation gives some individuals traits that help them survive a change in the environment (heat, drought, disease).
These survivors reproduce, so variation is the raw material for evolution.
Revision note — Heredity and variation
• Heredity: passing of traits from parents to offspring; variation: differences among individuals of a species.
• The study of heredity and variation is genetics.
• Sexual reproduction produces more variation — genes from two parents combine, and meiosis shuffles them.
• Asexual reproduction gives very little variation — only from small errors in DNA copying.
• Variants suited to the environment are kept by natural selection (Darwin).
• Example: bacteria that can withstand heat survive a heat wave better.
Also asked from this topic: the study of heredity and variation (genetics); the process that makes siblings of the same parents look different (meiosis).
Identical offspring are the opposite of variation — that is what asexual reproduction tends to produce.
RRB JE CBT-1 2024-25 – 18 December 2024 Shift 2 · Mendel's laws and experiments

Q62. What are the units of inheritance, which Mendel referred to as 'factors,' now called?

  1. (a) Chromosomes
  2. (b) Genes
  3. (c) Traits
  4. (d) DNA
Answer & solution

Answer: (b) Genes

Answer: Option 2 — Genes
Mendel said each trait is controlled by a pair of 'factors' passed from parents to offspring.
These factors are now called genes.
Revision note — Mendel and heredity
• Gregor Johann Mendel — the Father of Genetics; worked on the garden pea, Pisum sativum, with 7 pairs of contrasting traits.
• Monohybrid cross (tall × short): F1 all tall; F2 3 : 1 (phenotype), 1 : 2 : 1 (genotype).
• Dihybrid cross F2 ratio: 9 : 3 : 3 : 1.
• Law of dominance, law of segregation, law of independent assortment.
• A gene is a segment of DNA on a chromosome; different forms of a gene are alleles.
• The word gene was coined by Wilhelm Johannsen (1909).
Do not mix these up
• Gene vs chromosome vs DNA — DNA is the chemical; a chromosome is a long DNA thread; a gene is one functional segment of it that controls a trait.
Also asked from this topic: the law that the two alleles separate during gamete formation (law of segregation); the genotype of a short pea plant (tt).
RRB JE CBT-1 2024-25 – 18 December 2024 Shift 2 · Mendel's laws and experiments

Q63. According to Mendel, which trait appeared in F1 progeny on crossing tall pea plants with short pea plants?

  1. (a) Tall
  2. (b) Dwarf
  3. (c) Medium
  4. (d) Short
Answer & solution

Answer: (a) Tall

Answer: Option 1 — Tall
A cross of pure tall (TT) and pure short (tt) pea plants gives Tt plants in F1.
Tallness is dominant, so every F1 plant is tall — no medium or short plants appear.
Revision note — Mendel's monohybrid cross
• Gregor Mendel worked on the garden pea (Pisum sativum) and is the father of genetics.
• F1: all tall (Tt) — the trait that shows in F1 is dominant; the hidden one is recessive.
• F2 (selfing F1): phenotype 3 : 1 (tall : short), genotype 1 : 2 : 1 (TT : Tt : tt).
• The short trait reappears in F2, proving the recessive factor was not lost — it was only masked.
• Mendel studied 7 pairs of contrasting traits (height, seed shape, seed colour, flower colour …).
• Laws: law of dominance, law of segregation, law of independent assortment (dihybrid cross, F2 ratio 9 : 3 : 3 : 1).
Do not mix these up
• Dominance vs blending — F1 is fully tall, not medium; Mendel's result rejected the idea of blending.
Also asked from this topic: the genotype of a short pea plant (tt); the type of trait tallness is (dominant); the F2 phenotypic ratio of a monohybrid cross (3 : 1).

Q64. The genetic constitution of a child getting an X bearing sperm from the father will be:

  1. (a) 46+XX
  2. (b) 44+XX
  3. (c) 46+XY
  4. (d) 44+XY
Answer & solution

Answer: (b) 44+XX

Answer: Option 2 — 44+XX
The egg always carries 22 + X; an X-bearing sperm also carries 22 + X.
Together they give 44 autosomes + XX — the child is a girl.
Revision note — Sex determination in humans (Class 10)
• Humans have 46 chromosomes = 23 pairs: 22 pairs of autosomes + 1 pair of sex chromosomes.
• Female: 44 + XX; male: 44 + XY.
• Every egg carries 22 + X; a sperm carries either 22 + X or 22 + Y.
• The father's sperm decides the sex of the child — X-sperm ⇒ girl, Y-sperm ⇒ boy.
• Each fertilisation has a 50% chance of either sex.
• In some reptiles sex is decided by incubation temperature of the eggs, not by chromosomes.
Do not mix these up
• 46 vs 44 — 46 is the total count; 44 is the autosome count written before XX / XY.
Also asked from this topic: the number of pairs of autosomes in humans (22); the number of chromosomes in a normal human zygote (46).
46+XX would mean 48 chromosomes in all — the autosome count is 44.

Q65. What unique feature do the sex chromosomes in humans have compared to other chromosomes?

  1. (a) They are identical in males and females.
  2. (b) They are not always a perfect pair in males.
  3. (c) They are always perfectly paired.
  4. (d) They are the largest chromosomes in the body.
Answer & solution

Answer: (b) They are not always a perfect pair in males.

Answer: Option 2 — They are not always a perfect pair in males.
Women have a matched pair of sex chromosomes, XX.
Men have a mismatched pair, XY — the Y is much shorter than the X.
Revision note — Sex determination in humans
• Humans have 46 chromosomes in 23 pairs: 22 pairs of autosomes + 1 pair of sex chromosomes.
• Female: XX — all eggs carry X.
• Male: XY — half the sperms carry X, half carry Y.
• The father's sperm decides the sex of the child: X sperm ⇒ girl, Y sperm ⇒ boy.
• Chance of a boy or a girl in each birth = 50%.
• In some reptiles (turtles, crocodiles) sex is decided by the temperature at which eggs are kept.
Do not mix these up
• Autosomes vs sex chromosomes — autosomes are always in matched pairs in both sexes; only the sex-chromosome pair differs in males.
Also asked from this topic: the number of pairs of autosomes in humans (22).
RRB JE CBT-1 2024-25 – 17 December 2024 Shift 1 · Mendel's laws and experiments

Q66. Suppose a gardener wants to plant pea which should be of the dwarf varieties. What do you suggest for the choice of the parent plant seeds by the gardener?

  1. (a) All seeds should be of tall varieties.
  2. (b) All seeds should be of dwarf varieties.
  3. (c) All seeds should be of mixed varieties.
  4. (d) Any kind of seed can be used.
Answer & solution

Answer: (b) All seeds should be of dwarf varieties.

Answer: Option 2 — All seeds should be of dwarf varieties.
Dwarfness is a recessive trait, so a dwarf plant is always tt.
tt × tt gives only tt — every offspring is dwarf.
A tall parent could carry T and give tall plants.
Revision note — Mendel's monohybrid cross
• Mendel worked on the garden pea (Pisum sativum); tall (T) is dominant over dwarf (t).
• TT and Tt are both tall; only tt is dwarf.
• Tall (TT) × dwarf (tt) → F_(1) all tall (Tt).
• F_(1) selfed (Tt × Tt) → F_(2) phenotype 3 : 1 (tall : dwarf), genotype 1 : 2 : 1 (TT : Tt : tt).
• A recessive trait shows only when both copies are recessive — hence a dwarf plant breeds true.
• The dwarf trait reappears in F_(2) — the factor is not lost, only hidden in F_(1).
Do not mix these up
• Genotype vs phenotype — genotype is the gene pair (Tt); phenotype is what we see (tall).
Also asked from this topic: the allele combination that gives a short pea plant (tt); the type of trait tallness is in pea plants (dominant).

Q67. The first fundamental factor for evolution is:

  1. (a) competition among individuals
  2. (b) healthy offsprings
  3. (c) genetic variation
  4. (d) cell division for growth
Answer & solution

Answer: (c) genetic variation

Answer: Option 3 — genetic variation
Evolution can act only when individuals of a population differ from one another.
Those heritable differences (genetic variations) are the raw material on which natural selection works, so variation is the first and basic factor.
Revision note — Variation and evolution
• Variation arises mainly during reproduction — small errors in DNA copying and the mixing of genes in sexual reproduction.
• Sexual reproduction produces more variation than asexual reproduction.
• Variations that help survival are favoured by natural selection (Charles Darwin, On the Origin of Species, 1859).
• Genetic drift — chance changes in gene frequency, most marked in small populations.
• Accumulation of variations over many generations leads to speciation (new species).
• A mutation is a change in the DNA sequence; it is the ultimate source of new variation.
• Traits acquired during life (e.g. a body builder's muscles) are not inherited — they cause no evolution.
Do not mix these up
• Variation vs natural selection — variation supplies the differences; natural selection chooses among them.
Also asked from this topic: the process by which small heritable differences over generations produce new life forms (evolution); a change in the DNA sequence that alters genotype and phenotype (mutation).
RRB JE CBT-1 2024-25 – 17 December 2024 Shift 1 · Mendel's laws and experiments

Q68. Mendel had selected garden pea for certain favourable reasons. Which of the following is NOT a reason for his choice required for his experiments?

  1. (a) They produce many offsprings.
  2. (b) They have easily observable traits.
  3. (c) They can be self-pollinated and cross-pollinated.
  4. (d) They have a long generation time.
Answer & solution

Answer: (d) They have a long generation time.

Answer: Option 4 — They have a long generation time.
Garden pea has a short life cycle, so Mendel could study many generations quickly.
A long generation time would be a disadvantage, not a reason.
Revision note — Mendel and the garden pea
• Gregor Johann Mendel — the Father of Genetics; worked on garden pea (Pisum sativum) from 1856 to 1863.
• Reasons for the pea: short life cycle, many seeds (offspring), clear contrasting traits, and flowers that can be self-pollinated as well as cross-pollinated.
• He studied 7 pairs of contrasting traits — e.g. tall/dwarf plant, round/wrinkled seed, yellow/green seed.
• Monohybrid cross (tall × dwarf): F2 phenotype ratio 3 : 1, genotype ratio 1 : 2 : 1.
• Dihybrid cross: F2 phenotype ratio 9 : 3 : 3 : 1.
• Mendel's laws: Dominance, Segregation (purity of gametes), Independent Assortment.
Also asked from this topic: the allele combination that gives short pea plants (tt); the type of trait tallness is (dominant); the law of separation of alleles (Law of Segregation).
RRB JE CBT-1 2024-25 – 17 December 2024 Shift 1 · Genetic terms (dominant, recessive, genotype, phenotype)

Q69. What are the two versions of a gene controlling a trait called?

  1. (a) Alleles
  2. (b) Chromosomes
  3. (c) Mutations
  4. (d) Proteins
Answer & solution

Answer: (a) Alleles

Answer: Option 1 — Alleles
The two alternative forms of a gene that control one trait are its alleles.
In pea, T (tall) and t (dwarf) are alleles of the gene for plant height.
Revision note — Basic genetic terms
• Gene — a segment of DNA that codes for a protein; the unit of heredity.
• Homozygous — both alleles the same (TT or tt); heterozygous — different (Tt).
• Dominant allele shows even in a single copy (T); recessive shows only in a pair (tt).
• Genotype — the allele make-up (Tt); phenotype — the visible trait (tall).
• Alleles sit at the same position (locus) on a pair of homologous chromosomes.
• Humans have 46 chromosomes — 22 pairs of autosomes and 1 pair of sex chromosomes.
Do not mix these up
• Allele vs gene — the gene is the trait's instruction; alleles are its versions (T and t).
Also asked from this topic: the allele combination that gives short pea plants (tt); the law explaining separation of alleles during gamete formation (Law of Segregation).

Q70. What are the number of chromosomes in a human male germ cell?

  1. (a) 46 Chromosomes
  2. (b) 23 pairs of Chromosomes
  3. (c) 46 pairs of Chromosomes
  4. (d) 23 Chromosomes
Answer & solution

Answer: (d) 23 Chromosomes

Answer: Option 4 — 23 Chromosomes
A germ cell (gamete) is formed by meiosis, which halves the chromosome number.
So a human sperm carries only 23 single chromosomes (not pairs) — 22 autosomes + X or Y.
Revision note — Chromosomes and sex determination in humans
• Human body (somatic) cells are diploid: 46 chromosomes = 23 pairs.
• Of these, 22 pairs are autosomes and 1 pair is the sex chromosomes.
• Female: XX; male: XY.
• Gametes are haploid (n = 23): every egg carries 22 + X; a sperm carries 22 + X or 22 + Y.
• Fertilisation restores the number: sperm (23) + egg (23) = zygote (46).
• The sex of the child is decided by the father's sperm — a Y-sperm gives a boy, an X-sperm gives a girl.
Do not mix these up
• 23 chromosomes vs 23 pairs — a gamete has 23 unpaired chromosomes; 23 pairs (46) is a body cell.
Also asked from this topic: the number of pairs of autosomes in humans (22); the number of chromosomes a human zygote should have (46); the name for haploid reproductive cells like sperm and eggs (gametes).
RRB JE CBT-1 2024-25 – 17 December 2024 Shift 2 · Mendel's laws and experiments

Q71. Mendel studied traits such as flower colour and seed shape in pea plants. These traits are called as:

  1. (a) progeny units
  2. (b) visible characters
  3. (c) genetic codes
  4. (d) dominant characteristics
Answer & solution

Answer: (b) visible characters

Answer: Option 2 — visible characters
Mendel chose contrasting visible characters of the garden pea — tall/short plants, round/wrinkled seeds, violet/white flowers — that could be seen and counted in each generation.
NCERT calls these traits visible characters.
Revision note — Mendel's experiments on the garden pea
• Gregor Johann Mendel — the father of genetics; worked on Pisum sativum (garden pea).
• He studied 7 pairs of contrasting characters, e.g. tall/dwarf, round/wrinkled seed, yellow/green seed, violet/white flower.
• Monohybrid cross (tall × dwarf): F1 all tall; F2 tall : dwarf = 3 : 1; genotype ratio 1 : 2 : 1.
• Dihybrid cross: F2 = 9 : 3 : 3 : 1 — shows independent inheritance of traits.
• The trait seen in F1 is dominant (T); the hidden one is recessive (t); TT and Tt are tall, only tt is short.
• Mendel's "factors" are today's genes.
Do not mix these up
• Visible characters vs dominant characteristics — both forms of a character (e.g. violet and white) are visible characters; only one of them is dominant.
Also asked from this topic: the trait tallness shown by all F1 plants of a tall × dwarf cross (dominant trait); the genotype of a short pea plant (tt).
RRB JE CBT-1 2024-25 – 17 December 2024 Shift 3 · Mendel's laws and experiments

Q72. Which scientist(s) established the laws of Inheritance?

  1. (a) Charles Darwin
  2. (b) Thomas Hunt Morgan
  3. (c) Watson and Crick
  4. (d) Gregor Johann Mendel
Answer & solution

Answer: (d) Gregor Johann Mendel

Answer: Option 4 — Gregor Johann Mendel
Gregor Johann Mendel worked out the laws of inheritance from his experiments on garden pea (Pisum sativum) and published them in 1865–66.
Revision note — Mendel and the laws of inheritance
• Mendel was an Austrian monk; he is called the Father of Genetics.
• He studied 7 pairs of contrasting characters in pea (tall/dwarf, round/wrinkled seed, etc.).
• Law of Dominance — in a hybrid only the dominant trait shows in F_(1) (tall × dwarf → all tall).
• Law of Segregation — the two alleles of a gene separate during gamete formation; the monohybrid F_(2) ratio is 3 : 1.
• Law of Independent Assortment — two different traits are inherited independently; the dihybrid F_(2) ratio is 9 : 3 : 3 : 1.
• The term genetics was coined by William Bateson.
Do not mix these up
• Mendel vs Morgan vs Watson–Crick — Mendel gave the laws of inheritance; T. H. Morgan showed genes lie on chromosomes (fruit fly); Watson and Crick gave the double-helix model of DNA (1953).
• Mendel vs Darwin — Darwin gave the theory of evolution by natural selection, not the laws of heredity.
Also asked from this topic: the Mendel law that explains separation of alleles in gametes (Law of Segregation); the kind of trait tallness is in pea (dominant); the allele combination of a short pea plant (tt).

Q73. Which of the following factors is primarily responsible for survival of species?

  1. (a) Niche
  2. (b) Temperature
  3. (c) Mutation
  4. (d) Variations
Answer & solution

Answer: (d) Variations

Answer: Option 4 — Variations
Variations among individuals help a species survive: when the environment changes, some variants are better suited and survive and reproduce.
Without variation, one drastic change could wipe out the whole population.
Revision note — Variation and evolution (Class 10)
• Variation arises from inaccuracies in DNA copying and is increased by sexual reproduction (new combinations every generation).
• Asexual reproduction gives very little variation; sexual reproduction gives more.
• Example (NCERT): bacteria that can withstand heat survive a heat wave better.
• Natural selection (Darwin) favours variants suited to the environment; this drives evolution.
• Accumulated heritable variations over generations lead to new species (speciation).
• Changes in somatic (non-reproductive) tissue are acquired traits and are not inherited.
Do not mix these up
• Variation vs mutation — mutation is one source of change in DNA; variation is the whole range of differences among individuals, which is what selection acts on.
Also asked from this topic: what accumulates over generations to produce new life forms (variations — evolution of biodiversity); Darwin's descent with modification (differential survival and reproduction).

Q74. If a child inherits an Y chromosome from the father, what will be the sex of the child?

  1. (a) Hermaphrodite
  2. (b) Female
  3. (c) Cannot be determined
  4. (d) Male
Answer & solution

Answer: (d) Male

Answer: Option 4 — Male
The mother always gives an X. If the father's sperm carries Y, the zygote is XY — a male child.
Revision note — Sex determination in humans
• Humans have 46 chromosomes = 23 pairs: 22 pairs of autosomes + 1 pair of sex chromosomes.
• Females are XX; males are XY (the Y is shorter).
• Every egg carries X; half the sperms carry X and half carry Y.
• X sperm + egg → XX (girl); Y sperm + egg → XY (boy).
• So the sex of the child is decided by the father's sperm; the chance of a boy or a girl is 50 : 50.
• In some reptiles (turtles, some lizards) the temperature of incubation decides the sex.
Also asked from this topic: the number of pairs of autosomes in humans (22).

Q75. What determines the sex of a child in humans?

  1. (a) Genetic constitution
  2. (b) The fate of the embryo
  3. (c) The temperature at which fertilised eggs are placed
  4. (d) Environmental cues
Answer & solution

Answer: (a) Genetic constitution

Answer: Option 1 — Genetic constitution
In humans the sex of a child is genetically determined — by the sex chromosomes it inherits.
The mother always gives an X; the father's sperm gives either X (girl) or Y (boy).
Revision note — Sex determination
• Humans have 46 chromosomes = 23 pairs: 22 pairs of autosomes + 1 pair of sex chromosomes.
• Females are XX; males are XY — the Y chromosome is shorter.
• Every egg carries X; half the sperms carry X and half carry Y.
• X sperm + egg → XX (girl); Y sperm + egg → XY (boy) — the chance of each is 50 : 50.
• So the father's sperm decides the sex of the child.
• In some reptiles the temperature at which fertilised eggs are kept decides the sex; the snail changes sex — environmental control.
Do not mix these up
• Humans vs reptiles — humans: genetic (XX/XY); turtles and some lizards: incubation temperature.
Also asked from this topic: the number of pairs of autosomes in humans (22).
RRB JE CBT-1 2024-25 – 16 December 2024 Shift 3 · Mendel's laws and experiments

Q76. The knowledge of which two subjects played key role in formulating laws of Inheritance?

  1. (a) Maths and Science
  2. (b) Maths and History
  3. (c) Philosophy and Science
  4. (d) Geography and Philosophy
Answer & solution

Answer: (a) Maths and Science

Answer: Option 1 — Maths and Science
Gregor Johann Mendel used his knowledge of science (biology) and mathematics (statistics) to form the laws of inheritance.
He counted the offspring of each type and found fixed ratios such as 3 : 1 and 9 : 3 : 3 : 1.
Revision note — Mendel and the laws of inheritance
• Mendel (1822–1884) is the Father of Genetics; he worked on the garden pea (Pisum sativum).
• He studied seven pairs of contrasting traits — tall/dwarf, round/wrinkled seed, yellow/green seed and others.
• Monohybrid cross (tall × dwarf): F_(1) all tall; F_(2) ratio 3 : 1 (phenotype), 1 : 2 : 1 (genotype).
• Dihybrid cross: F_(2) phenotypic ratio 9 : 3 : 3 : 1.
• Law of dominance; law of segregation (the two alleles separate during gamete formation); law of independent assortment.
• TT and Tt plants are tall; only tt plants are dwarf — tallness is dominant.
Also asked from this topic: the law that explains separation of alleles during gamete formation (law of segregation); the kind of trait tallness is in pea plants (dominant); the genotype of a short pea plant (tt).

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