Q1. Which hormone is most directly associated with the regulation of mood and emotional balance?
- (a) Adrenaline
- (b) Thyroxine
- (c) Serotonin
- (d) Oxytocin
Answer & solution
Answer: (c) Serotonin
Serotonin is the chemical messenger that steadies mood, sleep and appetite; low levels are linked with depression and anxiety, which is why it is called the "feel-good" or "happy" hormone.
Adrenaline, thyroxine and oxytocin each have another primary job.
Revision note — Hormones that affect mood and stress
• Serotonin is made from the amino acid tryptophan; about 90 per cent of the body's serotonin is in the gut, the rest in the brain (raphe nuclei).
• Common anti-depressants (SSRIs) work by keeping more serotonin active at the synapse.
• Dopamine — the reward and motivation messenger; its loss in the brain causes Parkinson's disease.
• Melatonin — the sleep hormone from the pineal gland, released in darkness.
• Cortisol — the stress hormone from the adrenal cortex; adrenaline (epinephrine) from the adrenal medulla is the emergency or fight-or-flight hormone that raises heart rate and blood sugar.
• Thyroxine from the thyroid controls the metabolic rate; it needs iodine, and its shortage causes goitre.
• Oxytocin — the "love" or bonding hormone, released by the posterior pituitary; it triggers uterine contractions in childbirth and milk ejection.
• Endorphins are the body's natural pain-killers, released during exercise — the "runner's high".
Do not mix these up
• Serotonin vs dopamine — serotonin steadies mood; dopamine drives reward and pleasure-seeking.
• Adrenaline vs cortisol — both are adrenal stress hormones, but adrenaline (medulla) acts in seconds and cortisol (cortex) in hours.
• Oxytocin vs vasopressin — both come from the posterior pituitary, but vasopressin (ADH) controls water balance, not bonding.
Also asked from this topic: the gland that secretes adrenaline (adrenal gland); the element the thyroid needs to make thyroxine (iodine); the gland that secretes growth hormone (pituitary).